In 1870, after a brutal run-in with an outlaw in a brothel, Mike Blueberry becomes marshal in Arizona where he keeps the peace between Whites and Apaches but an influx of Indian gold treasure-hunters threatens to lead to violence.
In Bolivia, Butch Cassidy (now calling himself James Blackthorn) pines for one last sight of home, an adventure that aligns him with a young robber and makes the duo a target for gangs and lawmen alike.
In 1870s America, the fury of a notorious gang leader is unleashed when a peaceful American settler avenges the death of his family. Then as his cowardly fellow townspeople betray him, he is forced to hunt down the outlaws alone.
Honest and hard-working Texas rancher Homer Bannon has a conflict with his unscrupulous, selfish, arrogant and egotistical son Hud, who sank into alcoholism after accidentally killing his brother in a car crash.
Cole Thornton, a gunfighter for hire, joins forces with an old friend, Sheriff J.P. Hara. Together with an old Indian fighter and a gambler, they help a rancher and his family fight a rival rancher that is trying to steal their water.